Isotope dilution tandem mass spectrometric method for T4/T3
نویسندگان
چکیده
منابع مشابه
Comparison of two isotope dilution/mass spectrometric methods for determination of total serum cholesterol.
Isotope dilution/mass spectrometric methods for total serum cholesterol, developed separately at the Karolinska Institutet (KI) and the National Bureau of Standards (NBS), were compared by applying them to a common set of serum pools. A search for the cause of a systematic difference of a few percent in results from the two methods revealed that the KI cholesterol standard contained lathosterol...
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. A major activity in the 20 year collaboration between the Analytical Chemistry Division at NIST and the College of American Pathologists (CAP) has been the development of highly accurate and precise “definitive” methods for important clinical analytes in human serum. Definitive methods for organic analytes use isotope dilution/gas chromatography/ mass spectrometry and require a mass spectrome...
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Here, we report an enhanced throughput method for the diagnosis of human exposure to sulfur mustard. A hydroxyethylthioethyl (HETE) ester-adducted tripeptide, produced by pronase digestion of human serum albumin, was selected as the quantitative exposure biomarker. Cibacron Blue enrichment was developed from an established cartridge method into a 96-well plate format, increasing throughput and ...
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We have developed an improved reference measurement method for hemoglobin A1c (Hb A1c) 1 based on liquid chromatography–isotope dilution–tandem mass spectrometry (LC-ID-MS/MS) with traceability to the SI unit. The method has a small measurement uncertainty (MU) and gives results in good agreement with the accuracy-based IFCC reference method. Kaiser et al. (1 ) demonstrated the possibility of u...
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BACKGROUND An international working group convened by the American Diabetes Association (ADA) called for a reference measurement procedure for use in a trueness-based standardization project of insulin immunoassays. In view of this demand, we conducted a pilot study to investigate the feasibility of such a standardization project with our isotope dilution-liquid chromatography/tandem mass spect...
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ژورنال
عنوان ژورنال: Clinica Chimica Acta
سال: 2004
ISSN: 0009-8981
DOI: 10.1016/j.cccn.2004.01.007